Cationic phospholipids for transfection
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United States of America Patent
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Apr 6, 1999
Issued Date -
N/A
app pub date -
Jun 6, 1995
filing date -
Mar 29, 1994
priority date (Note) -
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Abstract
Cationic phospholipids and their use in treating pathogen-associated disease are disclosed. The class of phospholipids comprises the phosphotriester derivatives of phosphoglycerides and sphingolipids. Liposomes comprising one or more of the cationic phospholipids are effective in the lipofection of nuclidic acids and are therefore useful in methods of treating disease.
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