Bead linkers for immobilizing nucleic acids to solid supports
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United States of America Patent
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May 4, 1999
Grant Date -
N/A
app pub date -
Nov 6, 1996
filing date -
Nov 6, 1996
priority date (Note) -
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Abstract
Novel compositions comprised of at least one bead conjugated to a solid support and further conjugated to at least one nucleic acid and preferred methods for making the novel compositions are described. As compared to 'flat' surfaces, beads linked to a solid support provide an increased surface area for immobilization of nucleic acids. Furthermore, by selecting a bead with the desired functionality, a practitioner can select a functionalization chemistry for immobilizing nucleic acids, which is different from the chemistry of the solid support.
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