Ultra pure hemoglobin solutions and blood substitutes

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United States of America Patent

PATENT NO 5905141
SERIAL NO

08838514

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Abstract

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A blood substitute and plasma expander comprising a cross-linked, substantially endotoxin-free hemoglobin solution and process for preparing same. The process comprises fractionating whole blood, separating out a stromal-free, sterile hemoglobin solution, chromatographically separating endotoxins from said hemoglobin solution and crosslinking the resulting endotoxin-free hemoglobin solution.

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Patent Owner(s)

Patent OwnerAddress
OPK BIOTECH LLC11 HURLEY STREET CAMBRIDGE MA 02141

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Feola, Mario Lubbock, TX 6 244
Rausch, Carl W Providence, RI 23 380

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