Disposable cartridge and method for an assay of a biological sample
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United States of America Patent
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Jun 15, 1999
Issued Date -
N/A
app pub date -
Jan 14, 1997
filing date -
Sep 2, 1994
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A cartridge is provided to present a biological sample for analysis by an imaging instrument. The cartridge of the invention utilizes a series of channels, capillaries, reservoirs and stop junctions to precisely move a sample, reagent and diluent through the cartridge as a function of the sum of capillary, gravitational and low centrifugal forces. The operator applies a precise amount of sample to the cartridge; therefore, the cartridge fluidics need not meter the sample prior to dilution. A practical and cost effective cartridge and assay process is disclosed which overcomes many of the limitations of the prior art. Such a cartridge is especially useful with fixed volume assays which permit low centrifugal accelerations to move the fluids within the cartridge.
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