Polychelants containg amide bonds
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United States of America Patent
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Jun 22, 1999
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N/A
app pub date -
Oct 7, 1991
filing date -
Apr 7, 1989
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Abstract
There are provided polychelants and their metal chelates which are useful in diagnostic imaging and in radiotherapy and which comprise a plurality of macrocyclic chelant moieties, e.g. DOTA residues, conjugated to a dendritic polyamine backbone molecule, e.g. a starburst dendrimer. To produce a site-specific polychelate, one or more of the macrocyclic chelant carrying backbone molecules may be conjugated to a site-directed macromolecule, e.g. a protein.
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