Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
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United States of America Patent
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Jun 29, 1999
Issued Date -
N/A
app pub date -
Oct 10, 1997
filing date -
Jun 7, 1995
priority date (Note) -
Expired
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Abstract
The present invention relates to methods of enzymatically synthesizing oligonucleotides. In particular, it relates to the use of 3'-ribonucleotide primers which effectively serve to initiate oligonucleotide synthesis, and can also be easily cleaved from synthesis products and reused in subsequent synthesis reactions.
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