Stabilized monomeric protein compositions

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United States of America Patent

PATENT NO 5917021
SERIAL NO

08819033

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Abstract

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The present invention relates to a stabilized protein composition comprising a monomeric protein and a storage-stabilizing amount of sucrose, histidine or glycine, which is sufficient to inhibit aggregation of the protein molecules during freeze/thaw cycles, and methods therefor. More particularly, this invention relates to pharmaceutically-acceptable, single-chain antigen-binding protein compositions having increased frozen-storage stability, especially to freeze/thaw cycles.

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Patent Owner(s)

Patent OwnerAddress
MICROMET AGMUNICH GERMANY MUNICH BAVARIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lee, Lihsyng Stanford Princeton Junction, NJ 6 113

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