Oligonucleotides with activity against human immunodeficiency virus

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United States of America Patent

PATENT NO 5919701
SERIAL NO

08866958

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention features compounds and methods for inhibiting propagation of human immunodeficiency virus (HIV). Preferred HIV target sites are identified and oligonucleotides designed to hybridize to a target site are described. The preferred use of the oligonucleotides is as an anti-HIV agent to inhibit HIV propagation in a patient infected with HIV. Other uses of the present invention include detecting the presence of HIV by using the oligonucleotides as detection probes or amplification primers, and measuring the ability of an oligonucleotide to inhibit HIV propagation to evaluate its suitability as an anti-HIV agent for a phenotype of HIV or diagnose the presence of HIV in a patient.

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Patent Owner(s)

Patent OwnerAddress
GEN-PROBE INCORPORATED10210 GENETIC CENTER DRIVE ATTN PATENT DEPT SAN DIEGO CA 92121
BIOLUCENT LLC250 CAMPUS DRIVE MARLBOROUGH MA 01752
CYTYC CORPORATION250 CAMPUS DRIVE MARLBOROUGH MA 01752
HOLOGIC INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
SUROS SURGICAL SYSTEMS INC6100 TECHNOLOGY CENTER DRIVE NORTHWEST TECHNOLOGY CENTER INDIANAPOLIS IN 46278
THIRD WAVE TECHNOLOGIES INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP250 CAMPUS DRIVE MARLBOROUGH MA 01752

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Peterson, Todd C Chula Vista, CA 10 621
Velarde, Jr Jorge San Diego, CA 4 34

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