US Patent No: 5,925,016

Number of patents in Portfolio can not be more than 2000

Systems and methods for drug delivery including treating thrombosis by driving a drug or lytic agent through the thrombus by pressure

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ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

Systems and methods for treating thrombosis by driving the drugs or lytic agents through the thrombus by pressure, are disclosed. The system preferably comprises a guide catheter with an occlusion balloon for isolating the region proximal to the thrombus, a guide wire with an occlusion balloon for isolating the region distal to the thrombus and an infusion catheter for delivering drugs or other agents into the region distal to the thrombus under pressure. A lumen of the guide catheter is preferably provided to evacuate material proximal to the thrombus, decreasing the pressure in the proximal to the thrombus. The lumen can be coupled to a thrombus filter to remove thrombolytic material from the drug or lytic agent evacuated from the proximal region. The filtered drug or lytic agent can then be redelivered into the distal region. Recycling of the drug or lytic agent in this manner decreases the costs of the procedure. The systems and methods of the invention can be used to treat other blockages in lumens or vessels in the body or to deliver drugs or other agents to lumens, vessels or cavities within the body, as well.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MEDTRONIC AVE, INC.SANTA ROSA, CA321

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chornenky, Victor I Minnetonka, MN 54 1136
Forman, Michael R St. Paul, MN 43 2626

Cited Art

Patent Info (Count) # Cites Year
 
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LAKE REGION MANUFACTURING COMPANY, INC. (1)
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PIERPONT FAMILY LIMITED PARTNERSHIP (1)
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VASCULAR SOLUTIONS, INC. (1)
5,626,601 Vascular sealing apparatus and method 94 1995
 
Other [Check patent profile for assignment information] (1)
5,620,604 Dialysis system and method for removing toxic matter from the serum of the large intestine 1 1994

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (85)
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6,475,185 Occlusion device 22 2000
6,371,971 Guidewire filter and methods of use 211 2000
6,652,505 Guided filter with support wire and methods of use 96 2000
6,620,148 Filter flush system and methods of use 103 2000
6,676,682 Percutaneous catheter and guidewire having filter and medical device deployment capabilities 60 2000
7,094,249 Distal protection device and method 46 2000
6,544,280 Intravascular filter and method 105 2000
6,673,090 Percutaneous catheter and guidewire for filtering during ablation of myocardial or vascular tissue 54 2001
6,689,151 Variable wall thickness for delivery sheath housing 37 2001
6,840,950 Low profile emboli capture device 58 2001
6,537,295 Wire and lock mechanism 98 2001
6,616,681 Filter delivery and retrieval device 109 2001
6,755,847 Emboli capturing device and method of manufacture therefor 20 2001
7,153,320 Hydraulic controlled retractable tip filter retrieval catheter 4 2001
6,793,666 Distal protection mechanically attached filter cartridge 51 2001
7,169,165 Rapid exchange sheath for deployment of medical devices and methods of use 14 2002
6,936,059 Endovascular guidewire filter and methods of use 53 2002
6,932,830 Disc shaped filter 40 2002
6,997,938 Embolic protection device 44 2002
6,974,469 Distal protection device and method 50 2002
7,118,539 Articulating guide wire for embolic protection and methods of use 14 2002
7,226,464 Intravascular filter retrieval device having an actuatable dilator tip 5 2002
7,029,440 Distal protection filter and method of manufacture 35 2002
8,070,769 Inverted embolic protection filter 0 2002
7,060,082 Perfusion guidewire in combination with a distal filter 40 2002
7,585,309 Aortic filter 1 2002
7,001,406 Cartridge embolic protection filter and methods of use 40 2002
7,959,584 Dedicated distal protection guidewires 0 2002
6,663,652 Distal protection device and method 100 2002
7,326,224 Shaft and wire lock 0 2002
7,174,636 Method of making an embolic filter 10 2002
7,115,138 Sheath tip 3 2002
7,481,823 Multiple membrane embolic protection filter 0 2002
6,689,098 Occlusion device 1 2002
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6,991,642 Wire and lock mechanism 39 2003
7,163,549 Filter membrane manufacturing method 1 2003
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8,444,665 Filter flush system and methods of use 0 2003
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7,998,163 Expandable retrieval device 0 2003
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7,097,652 Variable wall thickness for delivery sheath housing 2 2003
7,320,698 Emboli capturing device and method of manufacture therefor 0 2004
8,241,315 Apparatus and method for treating occluded vasculature 0 2004
7,001,407 Distal protection mechanically attached filter cartridge 41 2004
7,621,904 Catheter with a pre-shaped distal tip 3 2004
8,236,024 Low profile emboli capture device 0 2004
8,262,690 Wire and lock mechanism 0 2004
8,038,696 Sheath for use with an embolic protection filter 0 2004
8,303,618 Intravascular filter and method 0 2004
7,563,272 Emboli filtration system and methods of use 1 2005
7,479,153 Endovascular guidewire filter and methods of use 0 2005
7,459,080 Flexible tube for cartridge filter 2 2005
7,204,464 Medical wire holder 1 2005
7,699,866 Emboli filtration system and methods of use 0 2005
7,691,123 Percutaneous catheter and guidewire having filter and medical device deployment capabilities 1 2005
7,785,344 Perfusion guidewire in combination with a distal filter 0 2006
7,762,403 Flexible tube for cartridge filter 1 2008
8,123,779 Embolic protection device 1 2009
8,444,669 Embolic filter delivery system and method 0 2009
7,896,861 Catheter with a pre-shaped distal tip 1 2009
8,007,510 Embolic protection filtering device that can be adapted to be advanced over a guidewire 0 2010
7,987,994 Flexible tube for cartridge filter 0 2010
8,292,829 Medical instrument with controlled torque transmission 0 2010
8,221,434 Retrieval device made of precursor alloy cable 0 2010
8,403,912 Catheter with a pre-shaped distal tip 0 2011
8,287,564 Embolic protection filtering device that can be adapted to be advanced over a guidewire 0 2011
 
INCEPT LLC (15)
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6,371,970 Vascular filter having articulation region and methods of use in the ascending aorta 196 1999
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6,663,651 Systems and methods for vascular filter retrieval 88 2001
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EKOS CORPORATION (8)
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RUBICON MEDICAL, INC. (6)
6,997,939 Methods, systems, and devices for deploying an embolic protection filter 46 2002
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6,936,060 Apparatus and methods for removing emboli during a surgical procedure 6 2002
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MEDRAD, INC. (5)
7,169,161 Guidewire having occlusive device and repeatably crimpable proximal end 9 2001
6,942,678 Gas inflation/evacuation system and sealing system for guidewire assembly having occlusive device 9 2001
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8,157,766 Torqueable kink-resistant guidewire 0 2009
 
MEDTRONIC AVE, INC. (5)
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CONCENTRIC MEDICAL, INC. (4)
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6,702,782 Large lumen balloon catheter 40 2001
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THE INVENTION SCIENCE FUND I, LLC (4)
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ADVANCED CARDIOVASCULAR SYSTEMS, INC. (3)
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KENSEY NASH CORPORATION (3)
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MEDTRONIC VASCULAR, INC. (3)
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7,052,500 Embolus extractor 15 2001
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LIFESCREEN SCIENCES LLC (2)
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BIO2 MEDICAL, INC. (1)
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VOLCANO THERAPEUTICS, INC. (1)
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8,460,336 Systems and methods for vascular filter retrieval 0 2011