Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus
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United States of America Patent
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Aug 3, 1999
Issued Date -
N/A
app pub date -
Jun 6, 1995
filing date -
Aug 26, 1991
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Abstract
Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.
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