Inhibitors of farnesyl-protein transferase

United States of America Patent

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Aug 17, 1999
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N/A
app pub date
Dec 22, 1997
filing date
Dec 30, 1996

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Expired

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Abstract

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

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MERCK & CO., INC.

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[Patents Count]

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Anthony, Neville J	Hatfield, PA	63	1842
Bell, Ian M	Harleysville, PA	87	704
deSolms, S Jane	Norristown, PA	38	710
Gomez, Robert P	Perkasie, PA	21	1024
Graham, Samuel L	Schwenksville, PA	57	1081
Kuo, Michelle Sparks	Gwynedd Valley, PA	2	46
Lumma, Jr William C	Pennsburg, PA	35	428
Perlow, Debra S	East Greenville, PA	8	129
Shaw, Anthony W	Lansdale, PA	40	343
Tran, Lekhanh O	Norristown, PA	10	309
Wai, John S	Harleysville, PA	50	840
Young, Steven D	Lansdale, PA	45	769

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Inhibitors of farnesyl-protein transferase

Number of patents in Portfolio can not be more than 2000

United States of America Patent

08995744

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PATENT NO	5939439
SERIAL NO	08995744
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08995744

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