PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
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United States of America Patent
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Aug 17, 1999
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app pub date -
Jun 4, 1998
filing date -
Jun 4, 1998
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Abstract
PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them suitable for encapsulation or solubilization of hydrophobic or water-insoluble materials; and they also form bioerodible matrices for the sustained release of active agents, especially when the POE block(s) contain at least one unit containing an .alpha.-hydroxy acid.
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