Localized intravascular delivery of growth factors for promotion of angiogenesis
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United States of America Patent
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Aug 24, 1999
Grant Date -
N/A
app pub date -
Nov 22, 1996
filing date -
Dec 22, 1995
priority date (Note) -
Expired
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Abstract
Angiogenesis in cardiac and other tissues is promoted by the transmural delivery of angiogenic factors such as VEGF, FGF, EGF, and PDGF, through blood vessels and other body lumens into the surrounding tissue. Usually, the angiogenic factor is delivered using a catheter having infusion parts at its distal end. Optionally, the distal end of the catheter is radially expanded to engage the infusion parts directly against the blood vessel wall.
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