Formulations and methods for providing prolonged local anesthesia
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United States of America Patent
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Aug 24, 1999
Grant Date -
N/A
app pub date -
Jun 16, 1997
filing date -
Jun 9, 1995
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible local anesthesia when implanted or injected in a patient, and a pharmaceutically acceptable, i.e., non-toxic, non-glucocorticoid augmenting agent effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without the augmenting agent.
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