Opto-acoustic transducer for medical applications
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United States of America Patent
Stats
-
Aug 31, 1999
Grant Date -
N/A
app pub date -
Apr 24, 1996
filing date -
Apr 24, 1996
priority date (Note) -
In Force
status (Latency Note)
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Abstract
This invention is an optically activated transducer for generating acoustic vibrations in a biological medium. The transducer is located at the end of a fiber optic which may be located within a catheter. Energy for operating the transducer is provided optically by laser light transmitted through the fiber optic to the transducer. Pulsed laser light is absorbed in the working fluid of the transducer to generate a thermal pressure and consequent adiabatic expansion of the transducer head such that it does work against the ambient medium. The transducer returns to its original state by a process of thermal cooling. The motion of the transducer within the ambient medium couples acoustic energy into the medium. By pulsing the laser at a high repetition rate (which may vary from CW to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus. The catheter may also incorporate anti-thrombolytic drug treatments as an adjunct therapy and it may be operated in conjunction with ultrasonic detection equipment for imaging and feedback control.

First Claim
Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | Total Patents |
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LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | LIVERMORE, CA | 1143 |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Benett, William | Livermore, CA | 7 | 372 |
Celliers, Peter | Berkeley, CA | 6 | 367 |
Da, Silva Luiz | Danville, CA | 12 | 860 |
Glinsky, Michael | Livermore, CA | 8 | 499 |
Krulevich, Peter | Pleasanton, CA | 2 | 111 |
Lee, Abraham | Walnut Creek, CA | 9 | 129 |
London, Richard | Orinda, CA | 8 | 480 |
Maitland, Duncan | Livermore, CA | 6 | 324 |
Matthews, Dennis | Moss Beach, CA | 10 | 850 |
Cited Art Landscape
Patent Info | (Count) | # Cites | Year |
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* 5342355 Energy delivering cap element for end of optic fiber conveying laser energy | 53 | 1992 | |
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* 4334321 Opto-acoustic transducer and telephone receiver | 88 | 1981 | |
* 4503564 Opto-acoustic transducer for a telephone receiver | 69 | 1982 | |
* 4576177 Catheter for removing arteriosclerotic plaque | 230 | 1983 | |
* 4589415 Method and system for fragmenting kidney stones | 115 | 1984 | |
* 4887605 Laser catheter delivery system for controlled atheroma ablation combining laser angioplasty and intra-arterial ultrasonic imagining | 202 | 1988 | |
* 4832024 Cardio-vascular catheter for shooting a laser beam | 183 | 1988 | |
* 5059200 Laser lithotripsy | 32 | 1990 | |
* 5152768 Electrohydraulic lithotripsy | 43 | 1991 | |
* 5377683 Ultrasound-laser surgery apparatus and method | 45 | 1991 | |
* 5324282 Surgical instrument with input power transducer | 39 | 1992 | |
* 5304171 Catheter devices and methods for delivering | 163 | 1993 | |
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* 5146917 Fibre-optic apparatus for the photodynamic treatment of tumors | 38 | 1991 | |
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* 5188632 Guidance and delivery system for high-energy pulsed laser light | 114 | 1990 | |
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* 5380273 Vibrating catheter | 114 | 1993 | |
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* 5324255 Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasopasm | 441 | 1992 | |
* 5368558 Ultrasonic ablation catheter device having endoscopic component and method of using same | 248 | 1993 | |
* 5474530 Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasospasm | 243 | 1994 | |
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* 5058570 Ultrasonic surgical apparatus | 115 | 1988 | |
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* 5116227 Process for cleaning and enlarging passages | 28 | 1991 | |
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* 5304115 Ultrasonic angioplasty device incorporating improved transmission member and ablation probe | 376 | 1991 | |
* 5326342 Ultrasonic angioplasty device incorporating all ultrasound transmission member made at least partially from a superlastic metal alloy | 207 | 1992 | |
* 5397301 Ultrasonic angioplasty device incorporating an ultrasound transmission member made at least partially from a superelastic metal alloy | 161 | 1993 | |
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* 5370609 Thrombectomy device | 288 | 1993 | |
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* 5219401 Apparatus for selective destruction of cells by implosion of gas bubbles | 165 | 1990 | |
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* 5026367 Laser angioplasty catheter and a method for use thereof | 64 | 1988 | |
* 5026366 Angioplasty catheter and method of use thereof | 472 | 1988 | |
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* 5193526 Laser light irradiation apparatus | 41 | 1992 | |
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* 5254112 Device for use in laser angioplasty | 104 | 1990 | |
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* 4913142 Catheter for laser angiosurgery | 202 | 1987 | |
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* 5254114 Medical laser delivery system with internally reflecting probe and method | 46 | 1991 | |
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* 5300066 Contact laser delivery system | 29 | 1992 | |
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* 4862886 Laser angioplasty | 260 | 1985 | |
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* 5397293 Ultrasonic device with sheath and transverse motion damping | 126 | 1992 | |
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* 5224942 Surgical method and apparatus utilizing laser energy for removing body tissue | 42 | 1992 | |
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* 5399158 Method of lysing thrombi | 40 | 1993 | |
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* 5109859 Ultrasound guided laser angioplasty | 307 | 1989 | |
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* 5353262 Optical transducer and method of use | 60 | 1993 | |
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* 5350375 Methods for laser induced fluorescence intensity feedback control during laser angioplasty | 107 | 1993 | |
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* 4900921 System and method for opto-acoustic liquid quantity measurement and transducer therefor | 34 | 1988 | |
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* 4852567 Laser tipped catheter | 133 | 1988 | |
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* 4770653 Laser angioplasty | 163 | 1987 | |
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* 4813930 Angioplasty guiding catheters and methods for performing angioplasty | 124 | 1987 | |
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* 4775361 Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport | 139 | 1986 | |
* 5354324 Laser induced platelet inhibition | 20 | 1990 | |
* 5472406 Apparatus and method for vasodilation | 137 | 1994 | |
* 5662590 Apparatus and method for vasodilation | 54 | 1995 | |
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* 5334207 Laser angioplasty device with magnetic direction control | 27 | 1993 | |
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* 4538609 Manipulator for laser knife | 46 | 1982 | |
* 5158560 Laser operating device for intracavitary surgery | 23 | 1990 | |
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* 4927427 Lithotriptor device for trapping and destroying concretions | 68 | 1989 | |
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* 5163421 In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging | 271 | 1989 | |
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* 5350377 Medical catheter using optical fibers that transmit both laser energy and ultrasonic imaging signals | 72 | 1992 | |
* 5486170 Medical catheter using optical fibers that transmit both laser energy and ultrasonic imaging signals | 96 | 1994 | |
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* 4844585 Optically excited vibratile transducer | 6 | 1988 | |
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* 5366490 Medical probe device and method | 549 | 1993 | |
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* 5217454 Laser delivery catheter | 61 | 1991 | |
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* 5029588 Laser catheter with imaging capability | 256 | 1989 | |
* 5010886 Medical probe assembly having combined ultrasonic imaging and laser ablation capabilities | 84 | 1989 | |
* 5005180 Laser catheter system | 70 | 1989 | |
* 5069664 Intravascular ultrasonic angioplasty probe | 163 | 1990 | |
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* 4834093 Dilation catheter and method | 57 | 1986 | |
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* 4932954 Apparatus for fragmentation of a solid body surrounded by a fluid | 41 | 1987 | |
* 5041121 Shock wave generator | 46 | 1989 | |
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* 4985028 Catheter | 56 | 1989 | |
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* 5041108 Method for laser treatment of body lumens | 118 | 1989 |
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7503895 Ultrasonic device for tissue ablation and sheath for use therewith | 142 | 2003 | |
7794414 Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes | 8 | 2004 | |
* 2007/0066,978 Ultrasound medical devices and related methods | 19 | 2006 | |
7775994 Ultrasound medical systems and related methods | 1 | 2006 | |
* 2008/0139,971 Ultrasound Medical Systems and Related Methods | 3 | 2006 | |
8790359 Medical systems and related methods | 3 | 2007 | |
8075504 Ultrasound medical systems and related methods | 0 | 2010 | |
* 2010/0268,127 Ultrasound Medical Systems and Related Methods | 1 | 2010 | |
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* 2008/0228,073 SYSTEM AND METHOD FOR OPTOACOUSTIC IMAGING OF PERIPHERAL TISSUES | 9 | 2008 | |
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* 6309352 Real time optoacoustic monitoring of changes in tissue properties | 57 | 1998 | |
6405069 Time-resolved optoacoustic method and system for noninvasive monitoring of glucose | 39 | 1999 | |
7430445 Noninvasive blood analysis by optical probing of the veins under the tongue | 9 | 2004 | |
* 2008/0255,433 OPTOACOUSTIC MONITORING OF MULTIPLE PARAMETERS | 30 | 2008 | |
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* 2008/0281,173 Noninvasive blood analysis by optical probing of the veins under the tongue | 0 | 2008 | |
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* 2008/0154,257 Real-time optoacoustic monitoring with electophysiologic catheters | 9 | 2006 | |
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* 7344528 Optic fiber probe | 31 | 2005 | |
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* 2007/0123,776 Ultrasonic probing device with distributed sensing elements | 8 | 2004 | |
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8184351 Amplified bimorph scanning mirror, optical system and method of scanning | 2 | 2009 | |
* 2010/0085,619 Amplified bimorph scanning mirror, optical system and method of scanning | 0 | 2009 | |
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* 2004/0258,258 Fluidic acoustic transducer | 0 | 2003 | |
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* 2009/0227,997 SYSTEM AND METHOD FOR PHOTOACOUSTIC IMAGING AND MONITORING OF LASER THERAPY | 37 | 2007 | |
* 2008/0123,083 System and Method for Photoacoustic Guided Diffuse Optical Imaging | 17 | 2007 | |
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* 2008/0221,647 SYSTEM AND METHOD FOR MONITORING PHOTODYNAMIC THERAPY | 25 | 2008 | |
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8182473 Cooling system for a photocosmetic device | 18 | 2006 | |
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8915948 Method and apparatus for photothermal treatment of tissue at depth | 1 | 2008 | |
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8002768 Light energy delivery head | 8 | 2010 | |
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* 2005/0015,123 Endovascular treatment of a blood vessel using a light source | 22 | 2004 | |
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6755821 System and method for stimulation and/or enhancement of myocardial angiogenesis | 39 | 1999 | |
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* 7300414 Transcranial ultrasound thrombolysis system and method of treating a stroke | 17 | 2000 | |
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* 2002/0045,890 Opto-acoustic thrombolysis | 95 | 2001 | |
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7935107 Heads for dermatology treatment | 21 | 2010 | |
8109924 Heads for dermatology treatment | 5 | 2011 | |
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* 7081113 Helical probe | 5 | 2003 | |
* 2004/0267,251 Helical probe | 10 | 2003 | |
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6547779 Flexible flow apparatus and method for the disruption of occlusions | 87 | 1999 | |
6527763 Flow apparatus for the disruption of occlusions | 43 | 2001 | |
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6368318 Opto-acoustic recanilization delivery system | 10 | 1998 | |
6210400 Flexible flow apparatus and method for the disruption of occlusions | 63 | 1998 | |
6440124 Flexible flow apparatus and method for the disruption of occlusions | 5 | 2000 | |
* 2005/0021,013 Photoacoustic removal of occlusions from blood vessels | 39 | 2002 | |
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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