(R)-5-bromo-N-(1-ethyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridinecarboxamide, process for producing the same and medicinal composition containing the same
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United States of America Patent
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Aug 31, 1999
Grant Date -
N/A
app pub date -
Jan 23, 1998
filing date -
Jul 28, 1995
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
This invention discloses a compound which is expressed by formula (I) below: ##STR1## or physiologically acceptable acid addition salts thereof. The claimed compound exhibits excellent antiemetic effect based on its potent serotonin S.sub.3 and dopamine D.sub.2 receptor antagonistic activities, and is useful for treatment or prophylaxis of various gastrointestinal symptoms which are associated with various diseases and drug administration.
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