US Patent No: 5,948,428

Number of patents in Portfolio can not be more than 2000

Compositions and therapeutic methods using morphogenic proteins and stimulatory factors

1 Status Updates

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention provides pharmaceutical compositions comprising a morphogenic protein stimulatory factor (MPSF) for improving the tissue inductive activity of morphogenic proteins, particularly those belonging to the BMP protein family. Methods for improving the tissue inductive activity of a morphogenic protein in a mammal using those compositions are provided. This invention also provides implantable morphogenic devices comprising a morphogenic protein and a MPSF disposed within a carrier, that are capable of inducing tissue formation in allogeneic and xenogeneic implants. Methods for inducing local tissue formation from a progenitor cell in a mammal using those devices are also provided. A method for accelerating allograft repair in a mammal using morphogenic devices is provided. This invention also provides a prosthetic device comprising a prosthesis coated with a morphogenic protein and a MPSF, and a method for promoting in vivo integration of an implantable prosthetic device to enhance the bond strength between the prosthesis and the existing target tissue at the joining site. Methods of treating tissue degenerative conditions in a mammal using the pharmaceutical compositions are also provided.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
MARIEL THERAPEUTICS, INC.NEW YORK, NY84

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lee, John C San Antonio, TX 52 1491
Yeh, Lee-Chuan C San Antonio, TX 17 723

Cited Art Landscape

Patent Info (Count) # Cites Year
 
STRYKER CORPORATION (7)
* 5,011,691 Osteogenic devices 191 1989
* 5,171,574 Bone collagen matrix for implants 107 1990
* 5,108,753 Osteogenic devices 127 1990
* 5,162,114 Bone collagen matrix for xenogenic implants 87 1990
* 5,344,654 Prosthetic devices having enhanced osteogenic properties 111 1992
* 5,324,819 Osteogenic proteins 99 1992
* 5,354,557 Osteogenic devices 109 1992
 
Bioscience Consultants (1)
* 5,531,791 Composition for repair of defects in osseous tissues, method of making, and prosthesis 154 1993
 
MARIEL THERAPEUTICS, INC. (1)
* 5,258,494 Osteogenic proteins 50 1992
 
WARSAW ORTHOPEDIC, INC. (1)
* 5,484,601 Flowable demineralized bone powder composition and its use in bone repair 69 1991
 
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (1)
* 5,461,034 Osteogenic growth polypeptides identified from regenerating bone marrow 29 1993
 
GENETICS INSTITUTE, LLC (1)
* 5,459,047 BMP-6 proteins 47 1994
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
ALLTECH ASSOCIATES, INC. (2)
6,998,042 Solid compositions for selective adsorption from complex mixtures 3 2004
* 2005/0003,428 Solid compositions for selective adsorption from complex mixtures 0 2004
 
Other [Check patent profile for assignment information] (8)
6,372,257 Compositions and methods for forming and strengthening bone 60 2000
* 2003/0147,860 Compositions and methods for forming and strengthening bone 21 2002
* 2004/0015,203 Multi-functional portable electro-medical device 7 2002
* 2004/0015,209 Electro-medical device for use with biologics 2 2002
* 2004/0127,402 Injectible composition and method for treating degenerative animal joints 0 2002
* 2006/0004,456 Intervertebral disc treatment devices and methods 16 2004
* 2009/0149,553 INJECTABLE RESORBABLE BONE GRAFT MATERIAL, POWDER FOR FORMING SAME AND METHODS RELATING THERETO FOR TREATING BONE DEFECTS 0 2009
9,511,115 Pharmaceutical compositions for treating or preventing bone conditions 0 2010
 
STRYKER CORPORATION (1)
* 2005/0152,883 Compositions and methods for ligament growth and repair 0 2004
 
Abbott Cardiovascular Systems Inc. (34)
7,964,210 Degradable polymeric implantable medical devices with a continuous phase and discrete phase 4 2006
8,603,530 Nanoshell therapy 2 2006
8,048,448 Nanoshells for drug delivery 5 2006
8,333,000 Methods for improving stent retention on a balloon catheter 5 2006
8,017,237 Nanoshells on polymers 5 2006
9,173,733 Tracheobronchial implantable medical device and methods of use 0 2006
8,099,849 Optimizing fracture toughness of polymeric stent 3 2006
8,343,530 Polymer-and polymer blend-bioceramic composite implantable medical devices 2 2006
8,486,135 Implantable medical devices fabricated from branched polymers 0 2007
8,262,723 Implantable medical devices fabricated from polymer blends with star-block copolymers 0 2007
8,034,287 Radiation sterilization of medical devices 13 2007
7,951,194 Bioabsorbable stent with radiopaque coating 9 2007
7,829,008 Fabricating a stent from a blow molded tube 9 2007
7,959,857 Radiation sterilization of medical devices 9 2007
8,293,260 Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices 3 2007
8,202,528 Implantable medical devices with elastomeric block copolymer coatings 4 2007
8,425,591 Methods of forming polymer-bioceramic composite medical devices with bioceramic particles 1 2007
8,535,372 Bioabsorbable stent with prohealing layer 7 2007
8,128,688 Carbon coating on an implantable device 7 2007
8,048,441 Nanobead releasing medical devices 4 2007
8,016,879 Drug delivery after biodegradation of the stent scaffolding 8 2007
7,901,452 Method to fabricate a stent having selected morphology to reduce restenosis 22 2007
7,823,263 Method of removing stent islands from a stent 1 2007
8,435,550 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 2 2008
8,585,754 Stent formed of a Biodegradable material 0 2012
8,925,177 Methods for improving stent retention on a balloon catheter 2 2012
8,592,036 Nanoshells on polymers 1 2012
9,259,341 Methods for improving stent retention on a balloon catheter 0 2013
8,808,342 Nanoshell therapy 1 2013
8,752,267 Method of making stents with radiopaque markers 0 2013
8,752,268 Method of making stents with radiopaque markers 2 2013
9,198,785 Crush recoverable polymer scaffolds 1 2013
9,038,260 Stent with radiopaque markers 1 2014
9,358,325 Stents with radiopaque markers 0 2015
 
CINVENTION AG (3)
* 2006/0177,379 Composition comprising an agent providing a signal, an implant material and a drug 119 2005
7,780,875 Composite materials containing carbon nanoparticles 14 2006
* 2007/0003,753 Medical devices comprising a reticulated composite material 33 2006
 
Advanced Cardiovascular Systems, Inc. (66)
7,470,283 Biodegradable drug delivery material for stent 14 2003
7,390,333 Biodegradable drug delivery material for stent 22 2003
7,258,891 Stent mounting assembly and a method of using the same to coat a stent 26 2003
7,186,789 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings 21 2003
7,285,304 Fluid treatment of a polymeric coating on an implantable medical device 45 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 72 2003
7,563,324 System and method for coating an implantable medical device 55 2003
7,699,890 Medicated porous metal prosthesis and a method of making the same 3 2004
7,553,377 Apparatus and method for electrostatic coating of an abluminal stent surface 22 2004
7,329,366 Method of polishing implantable medical devices to lower thrombogenecity and increase mechanical stability 16 2004
7,077,860 Method of reducing or eliminating thrombus formation 37 2004
8,568,469 Stent locking element and a method of securing a stent on a delivery system 0 2004
8,172,897 Polymer and metal composite implantable medical devices 6 2004
7,297,159 Selective coating of medical devices 12 2004
9,283,099 Stent-catheter assembly with a releasable connection for stent retention 0 2004
7,229,471 Compositions containing fast-leaching plasticizers for improved performance of medical devices 90 2004
8,778,256 Deformation of a polymer tube in the fabrication of a medical article 2 2004
8,173,062 Controlled deformation of a polymer tube in fabricating a medical article 7 2004
8,043,553 Controlled deformation of a polymer tube with a restraining surface in fabricating a medical article 18 2004
7,632,307 Abluminal, multilayer coating constructs for drug-delivery stents 14 2004
7,758,881 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 7 2005
7,381,048 Stents with profiles for gripping a balloon catheter and molds for fabricating stents 4 2005
7,291,166 Polymeric stent patterns 28 2005
7,875,283 Biodegradable polymers for use with implantable medical devices 14 2005
7,622,070 Method of manufacturing an implantable polymeric medical device 57 2005
7,875,233 Method of fabricating a biaxially oriented implantable medical device 15 2005
7,658,880 Polymeric stent polishing method and apparatus 8 2005
7,297,758 Method for extending shelf-life of constructs of semi-crystallizable polymers 3 2005
7,476,245 Polymeric stent patterns 12 2005
9,248,034 Controlled disintegrating implantable medical devices 0 2005
7,867,547 Selectively coating luminal surfaces of stents 0 2005
7,951,185 Delivery of a stent at an elevated temperature 19 2006
7,989,018 Fluid treatment of a polymeric coating on an implantable medical device 3 2006
8,747,878 Method of fabricating an implantable medical device by controlling crystalline structure 0 2006
8,003,156 Rotatable support elements for stents 15 2006
7,761,968 Method of crimping a polymeric stent 27 2006
7,959,940 Polymer-bioceramic composite implantable medical devices 5 2006
8,747,879 Method of fabricating an implantable medical device to reduce chance of late inflammatory response 0 2006
7,731,890 Methods of fabricating stents with enhanced fracture toughness 7 2006
9,072,820 Polymer composite stent with polymer particles 0 2006
7,794,776 Modification of polymer stents with radiation 10 2006
7,740,791 Method of fabricating a stent with features by blow molding 3 2006
7,998,404 Reduced temperature sterilization of stents 13 2006
7,757,543 Radio frequency identification monitoring of stents 2 2006
7,794,495 Controlled degradation of stents 13 2006
7,886,419 Stent crimping apparatus and method 3 2006
7,923,022 Degradable polymeric implantable medical devices with continuous phase and discrete phase 8 2006
7,842,737 Polymer blend-bioceramic composite implantable medical devices 6 2006
7,312,299 Bioabsorbabl, biobeneficial polyester polymers for stent coatings 3 2006
7,301,001 Bioabsorbable, biobeneficial polyester polymers for stent coatings 6 2006
8,197,879 Method for selectively coating surfaces of a stent 1 2007
7,604,700 Stent mandrel fixture and method for selectively coating surfaces of a stent 2 2007
7,662,326 Compositions containing fast-leaching plasticizers for improved performance of medical devices 1 2007
7,955,381 Polymer-bioceramic composite implantable medical device with different types of bioceramic particles 2 2007
8,470,014 Stent-catheter assembly with a releasable connection for stent retention 0 2007
8,109,994 Biodegradable drug delivery material for stent 4 2008
7,967,998 Method of polishing implantable medical devices to lower thrombogenecity and increase mechanical stability 2 2008
7,708,548 Molds for fabricating stents with profiles for gripping a balloon catheter 1 2008
8,846,070 Biologically degradable compositions for medical applications 0 2008
8,007,529 Medicated porous metal prosthesis 16 2008
8,414,642 Biodegradable stent of a polyorthoester polymer or a polyanhydride polymer 0 2008
8,293,367 Nanoshells on polymers 2 2011
8,741,379 Rotatable support elements for stents 2 2011
8,637,110 Rotatable support elements for stents 1 2011
8,596,215 Rotatable support elements for stents 1 2011
8,465,789 Rotatable support elements for stents 1 2011
 
SDGI HOLDINGS, INC. (1)
7,318,840 Intervertebral disc treatment devices and methods 120 2004
 
NOVOZYMES BIOPHARMA DK A/S (22)
7,045,318 Recombinant fusion proteins to growth hormone and serum albumin 22 2001
* 2003/0104,578 Recombinant fusion proteins to growth hormone and serum albumin 8 2001
6,686,179 Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 57 2001
7,094,577 Insulin and albumin fusion protein 15 2002
7,081,354 Interleukin and albumin fusion protein 8 2002
7,056,701 Hormone and albumin fusion protein 21 2002
7,041,478 G-CSF and albumin fusion protein 25 2002
6,972,322 Interferon and albumin fusion protein 23 2002
* 2003/0036,170 Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 7 2002
* 2003/0036,172 Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 6 2002
* 2003/0022,308 Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 8 2002
6,989,365 Methods of treatment with erythropoietin and albumin fusion protein 35 2003
6,987,006 Erythropoietin and albumin fusion protein, nucleic acids, and methods thereof 25 2003
* 2004/0086,976 Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 10 2003
7,141,547 Albumin fusion proteins comprising GLP-1 polypeptides 73 2004
7,482,013 Albumin fusion proteins 32 2005
* 2005/0266,533 Albumin fusion proteins 26 2005
7,435,410 Methods of treatment with interferson and albumin fusion protein 10 2005
* 2005/0239,167 Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 2 2005
7,550,432 Recombinant fusion proteins to growth hormone and serum albumin 5 2005
7,410,779 Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 12 2006
7,592,010 Albumin fusion proteins 20 2006
 
W.R. GRACE & CO.-CONN. (6)
6,802,966 Solid compositions for selective adsorption from complex mixtures 5 2001
6,987,079 Supported catalyst systems 6 2003
* 2003/0143,156 Novel supported catalyst systems 2 2003
7,314,845 Supported catalyst systems 0 2005
7,166,213 Solid compositions for selective adsorption from complex mixtures 2 2005
7,780,946 Supported catalyst systems 2 2007
 
MARIEL THERAPEUTICS, INC. (1)
* 7,026,292 Compositions and therapeutic methods using morphogenic proteins and stimulatory factors 21 1999
 
KENSEY NASH BVF TECHNOLOGY, LLC (6)
8,623,094 Devices and methods for treating defects in the tissue of a living being 2 2007
8,435,306 Devices and methods for treating defects in the tissue of a living being 2 2010
8,425,619 Devices and methods for treating defects in the tissue of a living being 2 2010
8,419,802 Devices and methods for treating defects in the tissue of a living being 4 2011
8,163,032 Devices and methods for treating defects in the tissue of a living being 5 2011
9,283,074 Devices and methods for treating defects in the tissue of a living being 0 2013
 
University of Erlangen-Nurnberg (2)
* 7,897,174 Formulation comprising bioactive agents and method of using same 0 2003
* 2003/0223,983 Formulation comprising bioactive agents and method of using same 6 2003
 
MARFLY 2, LP (2)
8,563,040 Compositions and methods for forming and strengthening bone 4 2009
* 2010/0136,120 COMPOSITIONS AND METHODS FOR FORMING AND STRENGTHENING BONE 1 2009
 
Marfly2, LP (1)
9,254,301 Compositions and methods for forming and strengthening bone 0 2013
 
ALLOSOURCE (3)
9,289,452 Consistent calcium content bone allograft systems and methods 1 2014
9,364,328 Multi-piece machine graft systems and methods 0 2014
9,486,556 Consistent calcium content bone allograft systems and methods 0 2016
 
LIFENET HEALTH (11)
7,498,040 Compositions for repair of defects in osseous tissues, and methods of making the same 26 2005
7,498,041 Composition for repair of defects in osseous tissues 31 2005
* 2007/0083,270 Orthopedic prosthetic devices containing compositions for repair of defects in osseous tissues 5 2005
* 2007/0082,057 Compositions for repair of defects in osseous tissues, and methods of making the same 2 2005
* 2007/0082,058 Composition for repair of defects in osseous tissues 3 2005
7,977,094 Compositions for repair of defects in osseous tissues, and methods of making the same 2 2007
* 2008/0069,893 Compositions for repair of defects in osseous tissues, and methods of making the same 1 2007
8,309,106 Composition for repair of defects in osseous tissues 7 2009
* 2009/0162,445 Composition for Repair of Defects in Osseous Tissues 0 2009
9,034,644 Compositions for repair of defects in osseous tissues, and methods of making the same 0 2011
9,408,875 Compositions for repair of defects in tissues, and methods of making the same 0 2015
 
OMEROS CORPORATION (3)
7,067,144 Compositions and methods for systemic inhibition of cartilage degradation 43 2003
* 2003/0235,589 Compositions and methods for systemic inhibition of cartilage degradation 9 2003
* 2006/0210,552 Compositions and methods for systemic inhibition of cartilage degradation 18 2006
 
WARSAW ORTHOPEDIC, INC. (8)
7,744,651 Compositions and methods for treating intervertebral discs with collagen-based materials 2 2005
7,713,303 Collagen-based materials and methods for augmenting intervertebral discs 3 2005
* 2005/0197,707 Collagen-based materials and methods for augmenting intervertebral discs 39 2005
8,399,619 Injectable collagen material 0 2006
8,118,779 Collagen delivery device 0 2006
* 2008/0004,703 Method of treating a patient using a collagen material 4 2006
7,731,981 Collagen-based materials and methods for treating synovial joints 2 2007
8,349,012 Intervertebral disc treatment devices and methods 0 2007
 
Canon Kabushiki Kaisha (1)
* 2004/0041,333 Sheet feeding apparatus and image forming apparatus 1 2003
 
The Regents of the University of California (17)
7,052,856 NELL-1 enhanced bone mineralization 10 1999
7,544,486 Nell peptide expression systems and bone formation activity of nell peptide 4 2004
* 2006/0292,670 Nell peptide expression systems and bone formation activity of nell peptide 6 2004
7,833,968 Pharmaceutical compositions for treating or preventing bone conditions 1 2006
7,776,361 NELL-1 enhanced bone mineralization 5 2006
* 2006/0228,392 NELL-1 enhanced bone mineralization 4 2006
7,687,462 Composition for promoting cartilage formation or repair comprising a nell gene product and method of treating cartilage-related conditions using such composition 22 2006
* 2007/0134,291 Composition for cartilage 43 2006
7,691,607 Expression system of NELL peptide 1 2006
* 2007/0128,697 Expression system of NELL peptide 1 2006
7,884,066 NELL-1 enhanced bone mineralization 12 2007
8,048,646 NELL peptide expression systems and bone formation activity of NELL peptide 1 2009
7,807,787 NELL-1 peptide 5 2009
8,053,412 NELL-1 peptides 1 2010
8,044,026 Composition for promoting cartilage formation or repair comprising a NELL gene product and method of treating cartilage-related conditions using such composition 1 2010
* 2010/0136,087 Composition for Promoting Cartilage Formation or Repair Comprising a NELL Gene Product and Method of Treating Cartilage-Related Conditions Using Such Composition 1 2010
8,207,120 NELL-1 enhanced bone mineralization 0 2011
 
PHILLIPS, FRANK M. (1)
8,697,139 Method of intervertebral disc treatment using articular chondrocyte cells 0 2004
 
SYNOVIS ORTHOPEDIC AND WOUNDCARE, INC. (2)
* 2007/0218,038 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED 2 2007
* 2009/0196,898 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED 0 2009
 
INTERNATIONAL REHABILITATIVE SCIENCES, INC. (5)
6,393,328 Multi-functional portable electro-medical device 28 2000
6,560,487 Electro-medical device for use with biologics 19 2000
6,675,048 Electro-medical device for use with biologics 16 2001
6,988,005 Multi-functional portable electro-medical device 21 2002
7,747,332 Electrical stimulation combined with a biologic to increase osteogenesis 1 2003
 
FRESENIUS KABI AB (1)
6,281,175 Medical emulsion for lubrication and delivery of drugs 11 2000
 
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (1)
* 2002/0022,266 Localized delivery to a target surface 5 2001
 
NUO THERAPEUTICS, INC. (1)
6,303,112 Enriched platelet wound healant 12 1999
 
AGNOVOS HEALTHCARE, LLC (6)
7,754,246 Composite bone graft substitute cement and articles produced therefrom 11 2006
8,685,464 Composite bone graft substitute cement and articles produced therefrom 1 2007
8,025,903 Composite bone graft substitute cement and articles produced therefrom 3 2007
9,180,224 Composite bone graft substitute cement and articles produced therefrom 0 2010
8,685,465 Composite bone graft substitute cement and articles produced therefrom 1 2011
9,446,170 Multiphasic bone graft substitute material 0 2014
 
WRIGHT MEDICAL TECHNOLOGY, INC. (15)
7,371,408 Bone graft substitute composition 6 1999
7,371,409 Bone graft substitute composition 10 2001
7,371,410 Bone graft substitute composition 4 2002
* 2002/0110,541 Bone graft substitute composition 3 2002
6,652,887 Bone graft substitute composition 28 2002
7,211,266 Bone graft substitute composition 4 2003
7,291,179 Bone graft substitute composition 4 2003
* 2003/0235,621 Bone graft substitute composition 2 2003
7,507,257 Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects 1 2004
* 2004/0220,681 Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects 19 2004
7,250,550 Synthetic bone substitute material 30 2004
8,657,952 Bone graft substitute composition 1 2007
7,766,972 Synthetic, malleable bone graft substitute material 1 2007
7,658,768 Bone graft substitute composition 12 2007
8,968,465 Bone graft substitute composition 0 2014
 
BOSTON SCIENTIFIC SCIMED, INC. (1)
6,391,832 Medical emulsion for lubrication and delivery of drugs 22 2001
 
Zimmer Orthobiologics, Inc. (5)
* 2008/0031,970 Method of Promoting Natural Bypass 1 2007
8,497,236 Implantable putty material 2 2008
8,742,072 Bone growth particles and osteoinductive composition thereof 1 2010
8,690,874 Composition and process for bone growth and repair 0 2010
8,613,938 Bone void fillers 2 2011
 
ABBOTT LABORATORIES VASCULAR ENTERPRISES LIMITED (1)
9,295,570 Cold-molding process for loading a stent onto a stent delivery system 0 2005
 
Ebara Technologies, Inc. (1)
7,971,333 Manufacturing process for polymetric stents 59 2006
 
KERAPLAST TECHNOLOGIES, LTD. (3)
6,379,690 Keratin-based hydrogel for biomedical applications and method of production 25 2000
6,849,092 Implantable prosthetic or tissue expanding device 19 2001
6,783,546 Implantable prosthetic or tissue expanding device 184 2001
 
Human Genome Sciences, Inc. (20)
6,994,857 Albumin fusion proteins 27 2001
6,946,134 Albumin fusion proteins 70 2001
6,926,898 Albumin fusion proteins 39 2001
6,905,688 Albumin fusion proteins 66 2001
* 2004/0171,123 ALBUMIN FUSION PROTEINS 6 2001
* 2003/0219,875 Albumin fusion proteins 10 2001
7,507,413 Albumin fusion proteins 8 2004
* 2005/0244,931 Albumin fusion proteins 19 2004
7,507,414 Albumin fusion proteins 5 2005
7,521,424 Albumin fusion proteins 17 2005
* 2006/0084,794 Albumin fusion proteins 24 2005
* 2006/0166,329 Albumin fusion proteins 2 2006
7,847,079 Albumin fusion proteins 6 2006
7,238,667 Albumin fusion proteins 23 2006
8,071,539 Albumin fusion proteins 2 2010
8,513,189 Albumin fusion proteins 0 2011
8,252,739 Albumin fusion proteins 1 2011
8,993,517 Albumin fusion proteins 0 2013
9,221,896 Albumin fusion proteins 0 2015
9,296,809 Albumin fusion proteins 0 2015
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (1)
* 2009/0269,388 ALLOGRAFT BONE COMPOSITION HAVING A GELATIN BINDER 5 2009
* Cited By Examiner