Process for synthesis of substituted sulphoxides

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United States of America Patent

PATENT NO 5948789
SERIAL NO

08492087

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Abstract

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A novel process for enantioselective synthesis of single enantiomers of omeprazole or its alkaline salts, of other optically pure substituted 2-(2-pyridinylmethyl-sulphinyl) -1H-benzimidazoles as well as of other structurally related sulphoxides or their alkaline salts. The claimed process is an asymmetric oxidation of a pro-chiral sulphide to the single enantiomers or an enantiomerically enriched form of the corresponding sulphoxide. The application also claims the enantiomeric sulphoxide products produced by the process and their use in medicine.

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Patent Owner(s)

Patent OwnerAddress
ASTRAZENECA AB151 85 SÖDERTÄLJE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cotton, Hanna Kristina .ANG.rsta, SE 1 65
Larsson, Magnus Erik Bromma, SE 1 65
Sorensen, Henrik Molnlycke, SE 10 130
Stenhede, Urban Jan Sodertalje, SE 1 65
von, Unge Sverker Per Oskar Fjar.ang.s, SE 1 65

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