Drug delivery

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 5954706
SERIAL NO

08473136

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention features a catheter and methods for delivering drug to tissue at a desired location of the wall of a body lumen. The catheter is constructed for insertion in a body lumen and has a catheter shaft and an expandable portion mounted on the catheter shaft. The expandable portion is expandable to a controlled pressure to fill the cross-section of the body lumen and press against the wall of the body lumen. In one embodiment, at least a portion of the exterior surface of the expandable portion is defined by a coating of a tenaciously adhered swellable hydrogel polymer. Incorporated in the hydrogel polymer is an aqueous solution of a preselected drug to be delivered to the tissue or plaque. The hydrogel polymer and drug are selected to allow rapid release of a desired dosage of the drug from the hydrogel polymer coating during compression of the hydrogel polymer coating against the wall of the lumen when the expandable portion is expanded. In other embodiments the polymer is released from the expandable portion in response to pressure, to coat the wall of the body lumen.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BOSTON SCIENTIFIC CORPORATIONMAPLE GROVE, MN287

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sahatjian, Ronald A Lexington, MA 87 5967

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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Adams and Reese LLP (1)
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TERUMO KABUSHIKI KAISHA (2)
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WISCONSIN ALUMNI RESEARCH FOUNDATION (1)
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MEDTRONIC, INC. (1)
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MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
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MEDTRONIC AVE, INC. (1)
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LUTHER MEDICAL PRODUCTS, INC. (1)
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BETH ISRAEL HOSPITAL ASSOCIATION (1)
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BECTON, DICKINSON AND COMPANY (1)
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Schneider (Europe) A.G. (1)
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CORDIS CORPORATION (3)
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GENZYME CORPORATION (1)
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C. R. BARD, INC. (1)
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BAXTER TRAVENOL LABORATORIES, INC., A CORP. OF DE (1)
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The Kendall Company (1)
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BOSTON SCIENTIFIC SCIMED, INC. (5)
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Kabushiki Kaisha Taiki (1)
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Lathrotec, Inc. (1)
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* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
DF VITAL HOLDINGS, LLC (4)
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OrbusNeich Medical, Inc. (2)
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Other [Check patent profile for assignment information] (14)
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ABBOTT CARDIOVASCULAR SYSTEMS INC. (5)
8226603 Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery 5 2008
8049061 Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery 11 2008
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9730820 Stent delivery system having a fibrous matrix covering with improved stent retention 0 2013
 
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MICRO THERAPEUTICS, INC. (1)
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SURMODICS, INC. (8)
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9066990 Preparation for restenosis prevention 0 2010
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9649476 Medical device for dispersing medicaments 0 2013
9302080 Medical device for dispersing medicaments 0 2014
9216272 Medical device for dispersing medicaments 0 2014
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COVIDIEN LP (14)
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8196584 Endotracheal cuff and technique for using the same 7 2006
8684175 Method for shipping and protecting an endotracheal tube with an inflated cuff 0 2006
8561614 Multi-layer cuffs for medical devices 0 2006
8307830 Endotracheal cuff and technique for using the same 2 2006
7950393 Endotracheal cuff and technique for using the same 2 2006
8750978 System and sensor for early detection of shock or perfusion failure and technique for using the same 1 2008
8590534 Cuff for use with medical tubing and method and apparatus for making the same 0 2009
8413659 Self-sizing adjustable endotracheal tube 1 2010
8813750 Self-sizing adjustable endotracheal tube 0 2010
8807136 Self-sizing adjustable endotracheal tube 0 2010
8636010 Endotracheal cuff and technique for using the same 3 2012
9032957 Endotracheal cuff and technique for using the same 1 2013
9289567 Endotracheal cuff and technique for using the same 0 2015
 
SCIMED LIFE SYSTEMS, INC. (1)
* 6409716 Drug delivery 188 1997
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
7238199 Method and apparatus for stent deployment with enhanced delivery of bioactive agents 53 2002
 
M.A. MED ALLIANCE SA (1)
9492594 Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs 0 2014
 
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (1)
* 2003/0181,973 Reduced restenosis drug containing stents 79 2002
 
ULRICH SPECK (2)
7750041 Preparation for the prophylaxis of restenosis 16 2001
8257305 Medical device for dispensing medicaments 14 2003
 
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (2)
8636721 Portable hand pump for evacuation of fluids 3 2004
9393353 Portable hand pump for evacuation of fluids 0 2014
 
Integrated Vascular Interventional Technologies, L.C., (“IVIT LC”) (1)
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Pentech Medical Devices Ltd. (1)
7410498 Polymeric stents and other surgical articles 6 2001
 
BATTELLE MEMORIAL INSTITUTE (3)
6979464 Reversible geling co-polymer and method of making 16 1998
7033571 Multiple stimulus reversible hydrogels 32 2003
* 2004/0096,508 Multiple stimulus reversible hydrogels 5 2003
 
PENTCH MEDICAL DEVICED LTD., (1)
* 2008/0300,675 POLYMERIC STENTS AND OTHER SURGICAL ARTICLES 5 2008
 
ETHICON, INC. (2)
6808518 Methods and devices for treating diseased blood vessels 28 2001
7611484 Methods and devices for treating diseased blood vessels 14 2004
 
REMON MEDICAL TECHNOLOGIES LTD. (1)
8303643 Method and device for electrochemical formation of therapeutic species in vivo 0 2010
 
Specialty Coating Systems, Inc. (2)
* 2006/0083,770 Medical devices and methods of preparation and use 4 2004
* 2007/0148,390 Fluorinated coatings 6 2005
 
SANOFI-AVENTIS DEUTSCHLAND GMBH (1)
* 2014/0236,098 Intraocular Injection Device 8 2012
 
COOK MEDICAL TECHNOLOGIES LLC (6)
8172793 Coated medical device 6 2005
8673387 Coated medical device 8 2009
9694162 Coated medical device 0 2009
* 2010/0049,309 COATED MEDICAL DEVICE 5 2009
8469943 Coated implantable medical device 1 2010
8974522 Coated medical device 0 2011
 
SURMODICS, INC. CORPORATION OF THE STATE OF MINNESOTA (1)
* 9669192 Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery 0 2015
 
LAKE REGION MANUFACTURING, INC. (1)
* 2011/0022,026 Methods and Devices for Delivering Drugs Using Drug-Delivery or Drug-Coated Guidewires 1 2009
 
Genetronics, Inc. (1)
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CYTYC CORPORATION (2)
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6537194 Catheter with permeable hydrogel membrane 38 2000
 
Biosynergetics, Inc. (5)
6738661 Apparatus and methods for the controllable modification of compound concentration in a tube 12 2000
7616989 Manufacturing methods for an apparatus for the controllable modification of compound concentration in a tube 0 2001
6985770 Apparatus for the controllable modification of compound concentration in a tube 11 2001
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8317760 Apparatus and methods for the controllable modification of compound concentration in a tube 0 2007
 
C. R. BARD, INC. (6)
8337475 Corporeal drainage system 7 2005
* 2006/0079,853 Corporeal drainage system 15 2005
8177772 Catheter connection systems 28 2006
8235971 Catheter connection systems 12 2010
8814839 Corporeal drainage system 2 2012
9295764 Corporeal drainage system 0 2014
 
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (1)
* 2002/0022,266 Localized delivery to a target surface 6 2001
 
FLUGEN, INC. (1)
8668675 Wearable drug delivery device having spring drive and sliding actuation mechanism 2 2011
 
ARROWHEAD MADISON INC. (1)
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EDWARDS LIFESCIENCES CORPORATION (1)
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Cardiac Pacemakers, Inc. (3)
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MEDIPACS, INC. (2)
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9500186 High surface area polymer actuator with gas mitigating components 0 2011
 
Lutonix, Inc. (30)
8414909 Drug releasing coatings for medical devices 25 2007
8414525 Drug releasing coatings for medical devices 24 2008
8425459 Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent 25 2008
8414526 Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids 28 2008
8430055 Methods and apparatuses for coating balloon catheters 22 2009
8414910 Drug releasing coatings for medical devices 27 2010
8403910 Drug releasing coatings for medical devices 25 2011
8404300 Drug releasing coatings for medical devices 26 2011
8366660 Drug releasing coatings for medical devices 25 2011
8366662 Drug releasing coatings for medical devices 24 2011
8998846 Drug releasing coatings for balloon catheters 7 2013
9180485 Methods and apparatuses for coating balloon catheters 0 2013
9033919 Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids 0 2013
9023371 Drug releasing coatings for medical devices 0 2013
9005161 Drug releasing coatings for medical devices 1 2013
8998847 Drug releasing coatings for medical devices 0 2013
8932561 Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent 7 2013
9402935 Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs 0 2013
9248220 Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent 0 2014
9314598 Drug releasing coatings for balloon catheters 0 2015
9283358 Drug releasing coatings for medical devices 0 2015
9289539 Drug releasing coatings for medical devices 7 2015
9314552 Drug releasing coatings for medical devices 0 2015
9289537 Medical device rapid drug releasing coatings comprising oils, fatty acids and/or lipids 0 2015
9770576 Methods and apparatuses for coating balloon catheters 0 2015
9694111 Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent 0 2016
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EnteroMedics Inc. (1)
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BOSTON SCIENTIFIC SCIMED, INC. (87)
6613025 Method and apparatus for diagnostic and therapeutic agent delivery 16 2000
8211455 Implantable or insertable medical devices for controlled delivery of a therapeutic agent 0 2002
7939094 Multiphase polymeric drug release region 14 2002
7105175 Implantable or insertable medical devices for controlled delivery of a therapeutic agent 50 2002
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* 2003/0235,603 Multiphase polymeric drug release region 40 2002
* 2003/0236,513 Implantable or insertable medical devices for controlled delivery of a therapeutic agent 79 2002
* 2003/0236,514 Implantable or insertable medical devices for controlled delivery of a therapeutic agent 105 2002
7060051 Multi-balloon catheter with hydrogel coating 122 2002
* 2004/0059,290 Multi-balloon catheter with hydrogel coating 66 2002
* 7066904 Triggered release hydrogel drug delivery system 141 2002
* 2003/0114,791 Triggered release hydrogel drug delivery system 48 2002
7491234 Medical devices for delivery of therapeutic agents 32 2002
* 2004/0106,987 Medical devices for delivery of therapeutic agents 117 2002
8313759 Implantable or insertable medical devices containing miscible polymer blends for controlled delivery of a therapeutic agent 0 2003
* 2004/0175,406 Implantable or insertable medical devices containing miscible polymer blends for controlled delivery of a therapeutic agent 45 2003
7241455 Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent 30 2003
* 2004/0202,691 Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent 24 2003
7762996 Method and apparatus for diagnostic and therapeutic agent delivery 20 2003
9114199 Implantable or insertable medical devices containing acrylic copolymer for controlled delivery of therapeutic agent 0 2003
8870814 Implantable or insertable medical devices containing silicone copolymer for controlled delivery of therapeutic agent 0 2003
7914805 Implantable or insertable medical devices containing radiation-treated polymer for improved delivery of therapeutic agent 0 2003
7357940 Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents 10 2003
* 2005/0025,802 Implantable or insertable medical devices containing acrylic copolymer for controlled delivery of therapeutic agent 58 2003
* 2005/0027,283 Implantable or insertable medical devices containing silicone copolymer for controlled delivery of therapeutic agent 57 2003
* 2005/0025,803 Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents 14 2003
* 2005/0025,801 Implantable or insertable medical devices containing radiation-treated polymer for improved delivery of therapeutic agent 24 2003
9498563 Medical articles having therapeutic-agent-containing regions formed from coalesced polymer particles 0 2004
* 2005/0239,508 Medical articles having therapeutic-agent-containing regions formed from coalesced polymer particles 6 2004
* 2006/0051,390 Medical devices having self-forming rate-controlling barrier for drug release 22 2004
8840660 Bioerodible endoprostheses and methods of making the same 7 2006
8089029 Bioabsorbable metal medical device and method of manufacture 4 2006
8187620 Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents 1 2006
8048150 Endoprosthesis having a fiber meshwork disposed thereon 10 2006
8815275 Coatings for medical devices comprising a therapeutic agent and a metallic material 1 2006
7901702 Implantable or insertable medical devices for controlled delivery of a therapeutic agent 0 2006
8067054 Stents with ceramic drug reservoir layer and methods of making and using the same 2 2007
7976915 Endoprosthesis with select ceramic morphology 1 2007
8771343 Medical devices with selective titanium oxide coatings 3 2007
7381418 Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent 33 2007
8002823 Endoprosthesis coating 2 2007
7942926 Endoprosthesis coating 2 2007
8815273 Drug eluting medical devices having porous layers 1 2007
7931683 Articles having ceramic coated surfaces 37 2007
8052743 Endoprosthesis with three-dimensional disintegration control 10 2007
8353949 Medical devices with drug-eluting coating 3 2007
8052744 Medical devices and methods of making the same 6 2007
8052745 Endoprosthesis 0 2007
8002821 Bioerodible metallic ENDOPROSTHESES 6 2007
8808726 Bioerodible endoprostheses and methods of making the same 1 2007
8128689 Bioerodible endoprosthesis with biostable inorganic layers 3 2007
8057534 Bioerodible endoprostheses and methods of making the same 12 2007
7981150 Endoprosthesis with coatings 8 2007
8216632 Endoprosthesis coating 1 2007
8029554 Stent with embedded material 10 2007
7938855 Deformable underlayer for stent 2 2007
8080055 Bioerodible endoprostheses and methods of making the same 8 2007
8431149 Coated medical devices for abluminal drug delivery 2 2008
8070797 Medical device with a porous surface for delivery of a therapeutic agent 7 2008
7998192 Endoprostheses 3 2008
8236046 Bioerodible endoprosthesis 7 2008
9284409 Endoprosthesis having a non-fouling surface 0 2008
8221822 Medical device coating by laser cladding 2 2008
7985252 Bioerodible endoprosthesis 6 2008
* 2009/0069,878 BIFURCATION POST-DILATATION BALLOON AND METHODS 5 2008
* 2008/0311,173 IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT 30 2008
8333795 Bulging balloon for bifurcation catheter assembly and methods 0 2008
8382824 Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides 0 2008
8361143 Medical devices for delivery of therapeutic agents 2 2009
* 2009/0138,076 MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENTS 10 2009
8071156 Endoprostheses 2 2009
8920491 Medical devices having a coating of inorganic material 0 2009
8932346 Medical devices having inorganic particle layers 1 2009
8287937 Endoprosthese 1 2009
8449603 Endoprosthesis coating 8 2009
8900292 Coating for medical device having increased surface area 4 2009
8231980 Medical implants including iridium oxide 0 2009
8267992 Self-buffering medical implants 10 2010
8066763 Drug-releasing stent with ceramic-containing layer 17 2010
8574615 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 8 2010
8668732 Surface treated bioerodible metal endoprostheses 2 2011
8889211 Coating process for drug delivery balloons using heat-induced rewrap memory 0 2011
9056152 Medical device with crystalline drug coating 0 2011
8669360 Methods of converting amorphous drug substance into crystalline form 0 2011
8715339 Bioerodible endoprostheses and methods of making the same 3 2011
* 2012/0203,323 METHOD AND SYSTEM FOR DELIVERY OF COATED IMPLANTS 0 2012
9248216 Medical devices for delivery of therapeutic agents 0 2013
 
Integrated Vascular Interventional Technologies, L.C. (IVIT, LC) (2)
6656151 Vascular access devices and systems 25 2000
6663590 Vascular occlusal balloons and related vascular access devices and systems 42 2001
 
BIOCOMPATIBLES UK LIMITED (3)
6746686 Coated implants 35 2001
6872225 Local drug delivery 12 2002
* 2004/0197,585 Coated implants 5 2003
 
W. L. GORE & ASSOCIATES, INC. (1)
9415193 Eluting medical devices 0 2012
 
THE SPECTRANETICS CORPORATION (12)
8257722 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 6 2008
9198968 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 0 2009
* 2010/0068,170 LOCAL DELIVERY OF WATER-SOLUBLE OR WATER-INSOLUBLE THERAPEUTIC AGENTS TO THE SURFACE OF BODY LUMENS 38 2009
8128951 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 6 2010
8114429 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 6 2010
8563023 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 2 2011
8491925 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 6 2011
8673332 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 0 2012
8734825 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 2 2013
9034362 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 0 2014
9132211 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 1 2014
9603973 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 0 2015
 
INTEGRATED VASCULAR INTERVENTIONAL TECHNOLOGIES (2)
7118546 Apparatus and methods for facilitating repeated vascular access 19 2003
* 2004/0019,315 Apparatus and methods for facilitating repeated vascular access 4 2003
 
DIONEX CORPORATION (1)
* 2003/0209,494 Continuously regenerated and integrated suppressor and detector for suppressed ion chromatography and method 0 2003
 
BOSTON SCIENTIFIC CORPORATION (2)
7291110 Catheter lesion diagnostics 6 2002
* 2003/0092,977 Catheter Lesion diagnostics 2 2002
* Cited By Examiner