Receptor-assisted combinatorial chemistry
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United States of America Patent
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Sep 28, 1999
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app pub date -
Feb 6, 1995
filing date -
Feb 6, 1995
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Abstract
This invention provides a method for preparing molecules that bind to a preselected receptor, whereby the receptor itself acts as an agent for either joining two ligand fragments to form a composite, tight binding ligand, or selects a composite ligand from a mixture in solution where ligand fragments are being joined and unjoined reversibly under equilibrium conditions.
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