Specific cyclooxygenase 2 inhibitor and anti-inflammatory agent

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United States of America Patent

PATENT NO 5958978
SERIAL NO

09029738

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Abstract

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The invention relates to a specific cyclooxygenase 2 inhibitor which comprises, as an active ingredient, 2-(2,6-dichloro-4-hydroxyanilino)phenylacetic acid represented by the following formula (1): ##STR1## or a salt thereof, as an anti-inflammatory agent. The compound specifically inhibits cyclooxygenase 2 without inhibiting cyclooxygenase 1 activity and thus it is low in toxicity and safe.

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Patent Owner(s)

Patent OwnerAddress
KABUSHIKI KAISHA YAKULT HONSHA1-10-30 KAIGAN MINATO-KU TOKYO 1058660
TEIKOKU HORMONE MFG CO LTDTOKYO JAPAN TOKYO METROPOLIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hashimoto, Shusuke Tokyo, JP 19 97
Matsuzaki, Takeshi Tokyo, JP 22 435
Yamazaki, Ryuta Tokyo, JP 16 49
Yokokura, Teruo Tokyo, JP 10 78

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