Oral cyclosporin formulations
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United States of America Patent
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-
Oct 5, 1999
Issued Date -
N/A
app pub date -
Oct 23, 1997
filing date -
Aug 25, 1995
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Improved oral cyclosporin formulations which have high bioavailability and are capable of administration in both liquid and hard capsule form are provided. In the subject formulations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formulations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.
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