Use of thermochromic liquid crystals in reflectometry based diagnostic methods
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United States of America Patent
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Oct 26, 1999
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app pub date -
Dec 23, 1996
filing date -
Dec 23, 1996
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Abstract
A method for improving the accuracy of temperature sensitive diagnostic assays which are carried out using reflectance spectrometers to detect color changes in a solid test system which has been contacted with a fluid test system suspected of containing an analyte whose presence and/or concentration is being sought. The method involves determining the temperature of the solid test material by measuring the reflectance of a thermochromic liquid crystal in close proximity to the solid test material and correcting the result of the assay for a change in temperature from a pre-selected nominal temperature.
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