Method and reagent for monitoring apoptosis and distinguishing apoptosis from necrosis
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United States of America Patent
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Nov 2, 1999
Issued Date -
N/A
app pub date -
Aug 20, 1997
filing date -
May 18, 1995
priority date (Note) -
Expired
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Abstract
The ability to determine the stage or pathway of cysteine proteases in a single cell assay has long been desired as a material event in apoptosis. The present invention relates to a method and assay reagents for determining enzyme activity and relating said activity to the apoptotic pathway. In addition, the method find utility in distinguishing apoptotic activity from necrotic activity.
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