Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
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United States of America Patent
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Nov 2, 1999
Issued Date -
N/A
app pub date -
Aug 29, 1995
filing date -
Jul 14, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A pharmaceutical composition for the nasal delivery of compounds useful for treating osteoporosis, comprising an effective amount of a physiologically active truncated analog of PTH or PTHrp, or salt thereof, in which amino acid residues (22-31) form an amphipathic .alpha.-helix, said residues (22-31) selected from (SEQ ID NOS: 85, 86, 26, 27, 28, 29, and 30); an absorption enhancer selected from the group consisting of dimethyl-.beta.-cyclodextrin and the bile acid surfactants; and water is provided.
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