Composition and method for making a biodegradable drug delivery stent
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United States of America Patent
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Nov 9, 1999
Grant Date -
N/A
app pub date -
Feb 7, 1997
filing date -
Feb 7, 1997
priority date (Note) -
Expired
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Abstract
A stent or vascular graft for supporting a blood vessel or organ lumen is coated with a biodegradable, resorbable and hemocompatible surface substrate. Biologically active microspheres which controllably release the biologically active agent into the vessel wall or organ to inhibit restenosis of the stent is embedded in the stent substrate. The biologically active microspheres include encapsulated PGE1 in a water soluble polyethylene glycol mix, which over a period of time dissolves and releases the PGE1 into the vessel wall or organ.
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