Dry analytical element and method for the detection of prostatic acid phosphatase
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United States of America Patent
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Nov 9, 1999
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app pub date -
May 20, 1992
filing date -
May 20, 1992
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Abstract
A dry analytical element has been prepared for the assay of prostatic acid phosphatase at a pH of from about 3 to about 6.5. The element can be a single porous spreading zone or a multilayer structure. Within the element is a relatively nonhygroscopic aromatic phosphate substrate for the analyte which produces a phenol reaction product. This product is reacted with a diazonium or tetrazolium salt, also in the element, to produce a chromophore for detection. A buffer in the element maintains it at the proper pH during the assay.
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