Importance

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Abstract

An allergy-diagnosing method comprising analyzing a sample that has been taken rectally from the large intestine of a patient who is suspected of being allergic, after having provoked the mucous membrane of the patient's large intestine rectally with an allergen against which the suspected allergy of the patient is directed. The method is characterized by: (a) taking the sample in the lumen of the large intestine; (b) determining an inflammation marker in the sample; and (c) taking an elevated marker quantity (elevated release) as an indication that the patient is allergic to the allergen concerned. The invention also relates to an instrument for rectal insertion into the rectum. The instrument is characterized in that it has an expandable part which surrounds a central channel that opens out on each side of the expandable part, and a separate channel through which expansion of the expandable part can be controlled such that when the instrument is applied in the rectum, the outer wall of the expandable part will be in direct contact with the mucous membrane of the rectum; and in that a diffusible allergen and optionally also a receptor for an inflammation marker is/are present on the outer defining surface of the expandable part.

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First Claim