Directed switch-mediated DNA recombination

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United States of America Patent

PATENT NO 5985615
SERIAL NO

08878166

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Abstract

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Switch regions derived from an immunoglobulin (Ig) gene are used to direct recombination between a targeting construct containing a promoter, a switch region (S.sub.1), and 2) a target locus minimally containing a promoter, a switch region (S.sub.2), and a target sequence.

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Patent Owner(s)

Patent OwnerAddress
AMGEN FREMONT INC6701 KAISER DRIVE FREMONT CA 94555

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gallo, Michael Lajos San Jose, CA 6 165
Jakobovits, Aya Menlo Park, CA 288 8747
Yang, Xiao-Ping Foster City, CA 3 162

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