Use of MOLT4 CD69 expression to determine the presence and activity of interferon inhibitors
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United States of America Patent
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Nov 23, 1999
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N/A
app pub date -
Aug 19, 1997
filing date -
Aug 19, 1996
priority date (Note) -
Expired
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Abstract
Disclosed is a method of determining the presence and activity of interferon inhibitors in a test sample, preferably human blood serum. The method includes the steps of culturing cells which express an interferon-inducible antigen in the presence of an interferon and then adding an aliquot of the cultured cells to a test sample and to a control sample. The expression of the interferon-inducible antigen is then measured in both the test sample and in the control sample and these two values compared to determine the presence and activity of interferon inhibitors in the test sample.
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