NSADI delivery employing a powdered hydrocolloid gum obtainable from higher plants
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United States of America Patent
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Nov 30, 1999
Issued Date -
N/A
app pub date -
Nov 13, 1997
filing date -
Jun 17, 1993
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An oral-delivery pharmaceutical composition for reducing the gastric irritation effect of an NSAID in the upper GI tract of a mammal. The composition includes (a) a mucosal protective amount of a pharmaceutically-acceptable hydrocolloid gum obtainable from higher plants, (b) a dispersion-enhancing amount of another excipient and (c) a therapeutically-effective amount of an NSAID. Also disclosed is a process for preparing the composition and a method for reducing the gastric irritation effect of the NSAID by administering the composition. Also, disclosed is a composition particularly useful for preparing an aqueous suspension.
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