Importance

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Abstract

An implant having an integrally-textured, hemocompatible blood-contacting surface and a method for producing the same is provided. The implantable device can include a device body having a textured surface and a predefined complex shape, such as a bladder or a generally U-shaped conduit. The device body can be composed of a first device material, and the textured surface can be formed of a second device material on the obverse side of the device. The textured surface can have multiple, blood-compatible structures integrally formed thereon. The structures can be fibrils that are suitable for a generally uniform biological layer to be established thereupon. The method for producing an implantable device can include the steps of fabricating a mold; applying a flock to the mold; introducing a conformable dissoluble material to the mold; removing the dissoluble material from the mold; removing the flock from the dissoluble material using a first solvent thereby creating a dissoluble device form having a form surface having multiple invaginations therein; applying a layer of a selected device material to the dissoluble device form thereby providing a device wall with the structures being integrally formed thereon; and removing the dissoluble device form from the device wall by liquefying the device form, thereby providing the implantable device.

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First Claim