Method and compositions for solubilization and stabilization of polypeptides, especially proteins
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United States of America Patent
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Dec 7, 1999
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N/A
app pub date -
Jun 29, 1989
filing date -
Oct 5, 1988
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Abstract
The invention provides a method for the solubilization and/or stabilization of polypeptides, especially proteins, using cyclodextrin selected from the group consisting of hydroxypropyl, hydroxyethyl, glucosyl, maltosyl and maltotriosyl derivatives of .beta.- and .gamma.-cyclodextrin. Solubilized and/or stabilized compositions comprising a polypeptide, especially a protein, and the selected cyclodextrin are also described.
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