Polynucleotide purification method
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United States of America Patent
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Dec 7, 1999
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N/A
app pub date -
Sep 15, 1997
filing date -
Sep 15, 1997
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Abstract
A method of purifying a hydrophobically substituted polynucleotide by reverse phase HPLC is described. The hydrophobic substituent may be removed from the polynucleotide under non-acidic conditions; the purification method is thus especially useful for acid sensitive polynucleotide analogs.
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