Universal linker for combinatorial synthesis
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United States of America Patent
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Dec 28, 1999
Grant Date -
N/A
app pub date -
Mar 16, 1998
filing date -
Mar 16, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A substrate for solid phase synthesis of the formula: ##STR1## is disclosed. Also disclosed are processes for preparing the substrate and intermediates useful therein. Among the novel intermediates are compounds of the formula: ##STR2## wherein t is 0 or 1; n is 3-20; R is OH, an activated ester or the residue of a solid support having a plurality of amino functionalities; A is --O--or --NH-- and Q is hydrogen or a protecting group for an amine or alcohol.
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