Growth differentiation factor-11 transgenic mice

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United States of America Patent

PATENT NO 6008434
SERIAL NO

08795671

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Abstract

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A transgenic mouse whose genome comprises a disruption of the endogenous growth differentiation factor-11 (GDF-11) gene is disclosed. Also disclosed are methods for making such mice. The mice exhibit a phenotype of increased muscle tissue.

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Patent Owner(s)

Patent OwnerAddress
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE720 RUTLAND AVENUE BALTIMORE MD 21218-5210

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lee, Se-Jin Baltimore, MD 164 2068
McPherron, Alexandra C Baltimore, MD 44 1591

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