Biodegradable blood-pool contrast agents
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United States of America Patent
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Jan 4, 2000
Grant Date -
N/A
app pub date -
Jan 21, 1997
filing date -
Apr 20, 1994
priority date (Note) -
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Abstract
The invention provides a blood pool contrast agent having an overall molecular weight of at least 10KD comprising a macrostructure which has bound thereto a plurality of opsonization inhibiting moieties and carries chelated ionic paramagnetic or heavy metal moieties, the chelant groups for said chelated moieties being macrocyclic where said macrostructure is liposomal.
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