Inhibitors of human plasmin derived from the kunitz domains

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United States of America Patent

PATENT NO 6010880
SERIAL NO

08676124

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Abstract

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This invention relates to novel mutants of the first Kunitz domain (K.sub.1) of the human lipoprotein-associated coagulation inhibitor (LACI) which inhibit plasmin. The invention also relates to other modified Kunitz domains that inhibit plasmin and to other plasmin inhibitors.

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Patent Owner(s)

Patent OwnerAddress
DYAX CORP300 SHIRE WAY LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ladner, Robert Charles Ijamsville, MD 83 1648
Markland, William Milford, MA 38 5584

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