Matrix metalloprotease inhibitors

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United States of America Patent

PATENT NO 6013792
SERIAL NO

08382818

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Abstract

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Compounds of formula (I): ##STR1## as single stereoisomers or mixtures thereof and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as interstitial collagenases, and are useful in the treatment of mammals having disease states alleviated by the inhibition of such matrix metalloproteases, for example arthritic diseases or bone resorption disease, such as osteoporosis.

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Patent Owner(s)

Patent OwnerAddress
SYNTEX (U S A ) INCPATENT LAW AND LICENSING DEPT MAILSTOP A2-200 3401 HILLVIEW AVENUE PALO ALTO CA 94304

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Castelhano, Arlindo Lucas Pleasanton, CA 10 174
Horne, Stephen Burlington, CA 13 67
Krantz, Alexander Menlo Park, CA 35 370
Liak, Teng Jiam Mississauga, CA 2 7
Yuan, Zhengyu Santa Clara, CA 34 236

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