Preparation of further diagnostic agents
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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-
Jan 18, 2000
Grant Date -
N/A
app pub date -
Jun 5, 1995
filing date -
Oct 10, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Microcapsules are prepared by a process comprising the steps of (i) spray-drying a solution or dispersion of a wall-forming material in order to obtain intermediate microcapsules and (ii) reducing the water-solubility of at least the outside of the intermediate microcaspsules. Suitable wall-forming materials include proteins such as albumin and gelatin. The microcapsules have walls of 40-500 nm thick and are useful in ultrasonic imaging. The control of median size, size distribution and degree of insolubilization and cross-linking of the wall-forming material allows novel microsphere preparations to be produced.
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