DNA methyltransferase genomic sequences and antisense oligonucleotides

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United States of America Patent

PATENT NO 6020318
SERIAL NO

08866340

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Abstract

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The invention provides recombinant nucleic acids comprising nucleic acid sequences from the genomic DNA methyltransferase gene. The invention further provides sequence information for such nucleic acid sequences. In addition, the invention provides antisense oligonucleotides complementary to special regions of the genomic DNA methyltransferase gene or its RNA transcript. Finally, the invention provides methods for using such antisense oligonucleotides as analytical and diagnostic tools, as potentiators of transgenic plant and animal studies and gene therapy approaches, and as potential therapeutic agents.

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Patent Owner(s)

Patent OwnerAddress
MCGILL UNIVERSITYMONTREAL QUEBEC H3A 3L8

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bigey, Pascal Clermont-Ferrand, FR 12 79
Ramchandani, Shyam Montreal, CA 3 8
Szyf, Moshe Cote St. Luc, CA 18 197

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