Nucleic acid respiratory syncytial virus vaccines
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United States of America Patent
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Feb 8, 2000
Issued Date -
N/A
app pub date -
Mar 27, 1998
filing date -
Jun 7, 1995
priority date (Note) -
Expired
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Abstract
Vectors containing a nucleotide sequence coding for an F protein of respiratory syncytial virus (RSV) and a promoter for such sequence, preferably a cytomegalovirus promoter, are described. Such vectors also may contain a further nucleotide sequence located adjacent to the RSV F protein enclosing sequence to enhance the immunoprotective ability of the RSV F protein when expressed in vivo. Such vectors may be used to immunize a host, including a human host, by administration thereto. Such vectors also may be used to produce antibodies for detection of RSV infection in a sample.
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