Method of selecting specific bacteriophages

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United States of America Patent

PATENT NO 6027930
SERIAL NO

08875069

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Abstract

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An improved method for selecting a molecule such as an antibody, antigen, peptide, protein or fragment thereof and its encoding sequence, which molecule is expressed together with a phage coat protein on the phages surface. The improvement is achieved through a new mutant filamentous helper phage which has retained the gene III promoter, whereas the gene III encoding sequence is deleted. Amplification of phage titer of 10.sup.6 times were achieved in M13-derived phages, when used for the selection of specific antibody.

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Patent Owner(s)

Patent OwnerAddress
BIOINVENT INTERNATIONAL ABSÖLVEGATAN 41 SE-223 70 LUND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borrebaeck, Carl A K Hjarup, SE 4 54

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