Pyrimidine derivatives and oligonucleotides containing same

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United States of America Patent

PATENT NO 6028183
SERIAL NO

08966392

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Abstract

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Compounds having structure (1) ##STR1## wherein R.sup.1 is --H a protecting group, a linker or a binding partner; and R.sup.2 and R.sup.34 are as defined in the specification. The invention also provides intermediates and methods make the structure (1) compounds, as well as methods to use the compounds as labels in diagnostic assays and to enhance binding to complementary bases.

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Patent Owner(s)

  • ISIS PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lin, Kuei-Ying Fremont, CA 46 3003
Matteucci, Mark D Portola Valley, CA 26 4826

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