Synthesis of cyclopropylacetylene
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United States of America Patent
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Feb 22, 2000
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N/A
app pub date -
Dec 15, 1997
filing date -
Dec 16, 1996
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Abstract
The present invention relates generally to novel methods for the synthesis of cyclopropylacetylene which is a reagent in the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one which is a useful human immunodeficiency virus (HIV) reverse transcriptase inhibitor.
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