Covalent attachment of nucleic acid molecules onto solid-phases via disulfide bonds
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United States of America Patent
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Feb 29, 2000
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app pub date -
Nov 21, 1997
filing date -
Mar 5, 1997
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Abstract
Methods for the covalent, specific and reversible immobilization of nucleic acid molecules onto solid-phases by means of a reversible disulfide bond for nucleic acid molecule array preparation are described. These methods can be used to prepare reusable nucleic acid molecule arrays with hilgh specificity and high efficiency.
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