Stable insulin formulations
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United States of America Patent
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Mar 7, 2000
Grant Date -
N/A
app pub date -
Jun 11, 1998
filing date -
Jun 13, 1997
priority date (Note) -
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Abstract
The present invention provides a monomeric insulin analog formulation stabilized against aggregation in which the buffering agent is either TRIS or arginine. The stable formulations of the present invention are useful for treating diabetes, and are particularly advantageous in treatment regimes requiring lengthy chemical and physical stability, such as, in continuous infusion systems.
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