Method for inhibiting cytokine secretion
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United States of America Patent
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Mar 7, 2000
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N/A
app pub date -
Sep 5, 1995
filing date -
Mar 10, 1993
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Abstract
A method for the prophylaxis and treatment of diseases induced by acceleration of secretion of cytokines (e.g. TNF-.alpha., IL-1, IL-6, IL-8, and IFN-.gamma.) which comprises administering a benzoheterocyclic compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are lower alkyl and X.sup.1 is halogen, R.sup.3 is lower alkyl, R.sup.4 is hydroxy, and X.sup.2 is halogen, or a pharmaceutically acceptable salt thereof.
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