Fluorogenic substrates for diagnosis and photodynamic treatment of tumors

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United States of America Patent

PATENT NO 6036941
SERIAL NO

09011347

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Abstract

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Fluorogenic substrates susceptible of fluorescence emission and photosensitization by enzyme transformation suitable for diagnosis and photodynamic treatment of tumors, consisting of fluorescent substances with photosensitization activity, chemically modified with a group quenching the fluorescence and photosensitization properties, the said quencher group being removable by the cell enzyme activity with restoration of the properties of fluorescence and photosensitization activity of the original substance.

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Patent Owner(s)

Patent OwnerAddress
CONSIGLIO NAZIONALE DELLE RICERCHEPIAZZALE ALDO MORO 7 ROMA 00185

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baglioni, Piero Fiesole, IT 13 90
Bottiroli, Giovanni Travaco' Siccomario, IT 1 38
Croce, Anna Cleta Torrazza Coste, IT 1 38
Monici, Monica Florence, IT 2 43

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