Matrix metalloprotease inhibitors

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United States of America Patent

PATENT NO 6037472
SERIAL NO

08343158

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds of formula (I) ##STR1## and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as stromelysin, gelatinase, matrilysin and collagenase, and are useful in the treatment of mammals having disease-states alleviated by the inhibition of such matrix metalloproteases.

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Patent Owner(s)

  • AGOURON PHARMACEUTICALS, INC.;SYNTEX (U.S.A.) INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bender, Steven Lee Oceanside, CA 16 701
Castelhano, Arlindo Lucas Pleasanton, CA 10 174
Deal, Judith Gail Temecula, CA 14 403
Horne, Stephen Burlington, CA 13 67
Liak, Teng J Mississauga, CA 5 37
Yuan, Zhengyu Santa Clara, CA 34 236

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